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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NRD1
All Species:
25.76
Human Site:
S638
Identified Species:
47.22
UniProt:
O43847
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43847
NP_001095132.1
1150
131572
S638
S
I
E
D
I
E
N
S
W
A
E
L
W
N
S
Chimpanzee
Pan troglodytes
XP_001140946
1151
131624
S639
S
I
E
D
I
E
N
S
W
A
E
L
W
N
S
Rhesus Macaque
Macaca mulatta
XP_001105075
1237
141727
S725
S
I
E
D
I
E
N
S
W
A
E
L
W
S
S
Dog
Lupus familis
XP_859649
1159
132371
S648
S
M
E
D
V
E
N
S
W
A
E
L
W
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHG1
1161
132873
S650
S
I
E
D
I
E
N
S
W
T
E
L
W
K
S
Rat
Rattus norvegicus
P47245
1161
132957
S650
S
I
E
D
I
E
N
S
W
T
E
L
W
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509651
859
96644
K380
W
G
N
A
E
T
L
K
H
E
P
R
A
K
N
Chicken
Gallus gallus
NP_001026455
1158
132212
Y646
S
V
E
D
I
D
K
Y
W
S
D
L
W
A
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694205
1091
124552
H574
S
T
E
D
I
E
Q
H
W
R
E
I
W
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22817
990
113666
S511
I
P
T
N
F
D
I
S
D
V
P
A
D
A
P
Honey Bee
Apis mellifera
XP_624437
1061
122950
E576
T
D
M
E
I
P
Q
E
W
I
E
C
W
R
T
Nematode Worm
Caenorhab. elegans
Q10040
856
98243
E377
P
Q
K
W
I
H
D
E
L
A
E
L
N
A
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06010
1027
117560
K548
S
T
N
F
K
V
D
K
I
D
G
I
K
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
84.3
94.1
N.A.
92.4
92.3
N.A.
47.4
76
N.A.
68.3
N.A.
29.1
38.7
25.1
N.A.
Protein Similarity:
100
99.8
85.9
96.7
N.A.
95.2
95.1
N.A.
54.6
85.7
N.A.
81.9
N.A.
47.8
58.8
42.5
N.A.
P-Site Identity:
100
100
93.3
73.3
N.A.
86.6
86.6
N.A.
0
53.3
N.A.
53.3
N.A.
6.6
26.6
26.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
6.6
80
N.A.
60
N.A.
20
46.6
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
39
0
8
8
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
8
0
62
0
16
16
0
8
8
8
0
8
0
0
% D
% Glu:
0
0
62
8
8
54
0
16
0
8
70
0
0
0
0
% E
% Phe:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% H
% Ile:
8
39
0
0
70
0
8
0
8
8
0
16
0
0
0
% I
% Lys:
0
0
8
0
8
0
8
16
0
0
0
0
8
31
8
% K
% Leu:
0
0
0
0
0
0
8
0
8
0
0
62
0
0
8
% L
% Met:
0
8
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
16
8
0
0
47
0
0
0
0
0
8
16
8
% N
% Pro:
8
8
0
0
0
8
0
0
0
0
16
0
0
8
8
% P
% Gln:
0
8
0
0
0
0
16
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
8
0
8
0
% R
% Ser:
70
0
0
0
0
0
0
54
0
8
0
0
0
8
47
% S
% Thr:
8
16
8
0
0
8
0
0
0
16
0
0
0
0
16
% T
% Val:
0
8
0
0
8
8
0
0
0
8
0
0
0
0
8
% V
% Trp:
8
0
0
8
0
0
0
0
70
0
0
0
70
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _